| Signal peptide(a) |
N |
Secretome P(b) |
0.817 |
| Function |
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity). . |
| GO - Molecular function |
- tubulin binding : IDA:MGI
|
| GO - Biological process |
- axonogenesis : IEA:Ensembl
- brain development : IEA:Ensembl
- establishment of skin barrier : IMP:CAFA
- hepatocyte growth factor receptor signaling pathway : IMP:CAFA
- intracellular signal transduction : TAS:ProtInc
- microtubule depolymerization : IDA:MGI
- mitotic cytokinesis : IMP:GO_Central
- mitotic spindle organization : IDA:MGI
- negative regulation of guanyl-nucleotide exchange factor activity : IMP:CAFA
- negative regulation of microtubule polymerization : IMP:CAFA
- negative regulation of Rho protein signal transduction : IMP:CAFA
- negative regulation of stress fiber assembly : IMP:CAFA
- negative regulation of thrombin-activated receptor signaling pathway : IMP:CAFA
- neuron projection development : IBA:GO_Central
- positive regulation of cellular component movement : IEA:Ensembl
- regulation of cytoskeleton organization : IBA:GO_Central
- regulation of microtubule polymerization or depolymerization : IMP:CAFA
- response to virus : IEP:UniProtKB
- signal transduction : NAS:ProtInc
|