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P15800

Laminin subunit beta-2 (P15800)

Uniprot ID P15800
Protein Name Laminin subunit beta-2
Gene Name Lamb2
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b)
Function Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
GO - Molecular function
  • extracellular matrix structural constituent : IBA:GO_Central
  • integrin binding : ISO:RGD
GO - Biological process
  • animal organ morphogenesis : IBA:GO_Central
  • astrocyte development : ISO:RGD
  • axon extension involved in regeneration : ISO:RGD
  • axon guidance : ISO:RGD
  • basement membrane assembly : IBA:GO_Central
  • cell migration : IBA:GO_Central
  • cell morphogenesis involved in differentiation : ISO:RGD
  • metanephric glomerular basement membrane development : ISO:RGD
  • metanephric glomerular visceral epithelial cell development : ISO:RGD
  • neuromuscular junction development : ISO:RGD
  • neuron projection development : ISO:RGD
  • retina development in camera-type eye : ISO:RGD
  • Schwann cell development : ISO:RGD
  • substrate adhesion-dependent cell spreading : IBA:GO_Central
  • synapse organization : ISO:RGD
  • tissue development : IBA:GO_Central
  • visual perception : ISO:RGD
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.