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P15502

Elastin (P15502)

Uniprot ID P15502
Protein Name Elastin
Gene Name ELN
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.155
Function Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity). .
GO - Molecular function
  • extracellular matrix structural constituent : TAS:ProtInc
GO - Biological process
  • animal organ morphogenesis : TAS:ProtInc
  • blood circulation : TAS:ProtInc
  • cell proliferation : TAS:ProtInc
  • extracellular matrix organization : TAS:Reactome
  • respiratory gaseous exchange : TAS:ProtInc
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.