| Signal peptide(a) |
Y |
Secretome P(b) |
0.94 |
| Function |
As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L. |
| GO - Molecular function |
- cysteine-type endopeptidase inhibitor activity : TAS:RGD
- peptidase inhibitor activity : IDA:RGD
- protease binding : IDA:RGD
|
| GO - Biological process |
- apoptotic process : IEP:RGD
- brain development : IEP:RGD
- cell activation : IEP:RGD
- cellular response to hydrogen peroxide : IEP:RGD
- cellular response to oxidative stress : IEP:RGD
- circadian sleep/wake cycle, REM sleep : IEP:RGD
- embryo implantation : IEP:RGD
- eye development : IEP:RGD
- male gonad development : IEP:RGD
- negative regulation of cell death : IMP:RGD
- positive regulation of cell proliferation : IDA:RGD
- positive regulation of DNA replication : IDA:RGD
- regulation of programmed cell death : IMP:RGD
- response to axon injury : IEP:RGD
- response to carbohydrate : IEP:RGD
- response to drug : IEP:RGD
- response to estradiol : IEP:RGD
- response to hypoxia : IEP:RGD
- response to inorganic substance : IEP:RGD
- response to nutrient levels : IEP:RGD
- response to organic cyclic compound : IEP:RGD
- response to oxidative stress : IMP:RGD
- response to toxic substance : IEP:RGD
- salivary gland development : IEP:RGD
- Sertoli cell development : IEP:RGD
|