60S ribosomal protein L7 (P14148)

Uniprot ID P14148
Protein Name 60S ribosomal protein L7
Gene Name Rpl7
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.396
Function Component of the large ribosomal subunit (By similarity). Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity). .
GO - Molecular function
  • 5S rRNA binding : ISO:MGI
  • DNA binding : ISO:MGI
  • mRNA binding : ISO:MGI
  • protein homodimerization activity : ISO:MGI
  • RNA binding : IBA:GO_Central
  • structural constituent of ribosome : IBA:GO_Central
GO - Biological process
  • cytoplasmic translation : IBA:GO_Central
  • maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) : IBA:GO_Central
  • ribosomal large subunit biogenesis : ISO:MGI
  • rRNA processing : ISO:MGI
  • translation : IC:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.