Protein CTLA-2-alpha (P12399)

Uniprot ID P12399
Protein Name Protein CTLA-2-alpha
Gene Name Ctla2a
Species Mus musculus (Mouse)
Signal peptide(a) Y Secretome P(b) 0.895
Function Not known, expressed in activated T-cell.
GO - Molecular function
  • cysteine-type peptidase activity : IEA:InterPro
GO - Biological process
  • negative regulation of inflammatory response : IDA:MGI
  • negative regulation of protein processing : IMP:MGI
  • regulation of regulatory T cell differentiation : IMP:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.