Collagen alpha-1(XI) chain (P12107)

Uniprot ID P12107
Protein Name Collagen alpha-1(XI) chain
Gene Name COL11A1
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.048
Function May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.
GO - Molecular function
  • extracellular matrix binding : NAS:UniProtKB
  • extracellular matrix structural constituent : IBA:GO_Central
  • heparan sulfate binding : IEA:Ensembl
  • heparin binding : IEA:Ensembl
  • metal ion binding : IEA:UniProtKB-KW
  • protein binding, bridging : NAS:UniProtKB
GO - Biological process
  • cartilage condensation : IEA:Ensembl
  • chondrocyte development : IEA:Ensembl
  • collagen fibril organization : NAS:UniProtKB
  • detection of mechanical stimulus involved in sensory perception of sound : IMP:UniProtKB
  • embryonic skeletal system morphogenesis : IEA:Ensembl
  • endodermal cell differentiation : IEP:UniProtKB
  • extracellular matrix organization : IBA:GO_Central
  • inner ear morphogenesis : IEA:Ensembl
  • ossification : IEA:Ensembl
  • proteoglycan metabolic process : IEA:Ensembl
  • sensory perception of sound : IMP:UniProtKB
  • tendon development : IEA:Ensembl
  • ventricular cardiac muscle tissue morphogenesis : IEA:Ensembl
  • visual perception : IMP:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.