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P11598

Protein disulfide-isomerase A3 (P11598)

Uniprot ID P11598
Protein Name Protein disulfide-isomerase A3
Gene Name Pdia3
Species Rattus norvegicus (Rat)
Basic Information Experiments (3) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b)
Function
GO - Molecular function
  • identical protein binding : ISO:RGD
  • MHC class I protein binding : IDA:RGD
  • peptidase activity : IDA:RGD
  • peptide disulfide oxidoreductase activity : ISO:RGD
  • protein disulfide isomerase activity : IBA:GO_Central
  • protein-disulfide reductase (glutathione) activity : IMP:RGD
GO - Biological process
  • cell redox homeostasis : IEA:InterPro
  • cellular response to interleukin-7 : ISO:RGD
  • cellular response to nonylphenol : IEP:RGD
  • cellular response to transforming growth factor beta stimulus : IEP:RGD
  • cellular response to vitamin D : IDA:RGD
  • circadian rhythm : IEP:RGD
  • positive regulation of extrinsic apoptotic signaling pathway : ISO:RGD
  • positive regulation of protein folding : IDA:RGD
  • protein folding : IBA:GO_Central
  • response to benzene : IEP:RGD
  • response to endoplasmic reticulum stress : IBA:GO_Central
  • response to ethanol : IEP:RGD
  • response to genistein : IEP:RGD
  • response to hyperoxia : IEP:RGD
  • response to hypoxia : IEP:RGD
  • response to ischemia : IEP:RGD
  • response to leptin : IEP:RGD
  • response to nutrient levels : IEP:RGD
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.