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P11348

Dihydropteridine reductase (P11348)

Uniprot ID P11348
Protein Name Dihydropteridine reductase
Gene Name Qdpr
Species Rattus norvegicus (Rat)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function The product of this enzyme, tetrahydrobiopterin (BH-4), is an essential cofactor for phenylalanine, tyrosine, and tryptophan hydroxylases.
GO - Molecular function
  • 6,7-dihydropteridine reductase activity : IDA:RGD
  • identical protein binding : IPI:RGD
  • NADH binding : IPI:RGD
  • NADPH binding : IMP:RGD
GO - Biological process
  • cellular response to drug : IEP:RGD
  • L-phenylalanine catabolic process : IEP:RGD
  • liver development : IEP:RGD
  • response to aluminum ion : IEP:RGD
  • response to glucagon : IEP:RGD
  • response to lead ion : IEP:RGD
  • tetrahydrobiopterin biosynthetic process : IDA:RGD
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.