Signal peptide(a) |
Y |
Secretome P(b) |
0.704 |
Function |
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity. |
GO - Molecular function |
- cytokine activity : NAS:UniProtKB
- extracellular matrix binding : IDA:MGI
|
GO - Biological process |
- androgen catabolic process : ISO:MGI
- biomineral tissue development : IEA:UniProtKB-KW
- cell adhesion : ISO:MGI
- cellular response to fluid shear stress : IDA:MGI
- cellular response to leukemia inhibitory factor : IEP:MGI
- cellular response to testosterone stimulus : ISO:MGI
- negative regulation of apoptotic process : NAS:UniProtKB
- neutrophil chemotaxis : IDA:MGI
- osteoblast differentiation : ISO:MGI
- positive regulation of bone resorption : ISO:MGI
- positive regulation of cell-substrate adhesion : IDA:MGI
- positive regulation of estradiol secretion : ISO:MGI
- positive regulation of transcription, DNA-templated : ISO:MGI
- response to organic substance : ISO:MGI
- response to steroid hormone : ISO:MGI
- response to vitamin D : ISO:MGI
|