Glutathione S-transferase Mu 1 (P10649)

Uniprot ID P10649
Protein Name Glutathione S-transferase Mu 1
Gene Name Gstm1
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.799
Function Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
GO - Molecular function
  • glutathione binding : ISO:MGI
  • glutathione transferase activity : ISO:MGI
  • identical protein binding : ISO:MGI
  • nickel cation binding : ISO:MGI
  • protein heterodimerization activity : IDA:MGI
  • protein homodimerization activity : IDA:MGI
  • protein kinase binding : ISO:MGI
  • steroid binding : ISO:MGI
GO - Biological process
  • cellular response to drug : IDA:MGI
  • glutathione metabolic process : ISO:MGI
  • xenobiotic catabolic process : ISO:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.