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P10605

Cathepsin B (P10605)

Uniprot ID P10605
Protein Name Cathepsin B
Gene Name Ctsb
Species Mus musculus (Mouse)
Basic Information Experiments (9) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.796
Function Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
GO - Molecular function
  • collagen binding : ISO:MGI
  • cysteine-type endopeptidase activity : ISO:MGI
  • cysteine-type peptidase activity : ISO:MGI
  • endopeptidase activity : ISO:MGI
  • kininogen binding : ISO:MGI
  • peptidase activity : ISO:MGI
  • peptide binding : ISO:MGI
  • protein self-association : ISO:MGI
  • protein-containing complex binding : ISO:MGI
  • proteoglycan binding : ISO:MGI
GO - Biological process
  • cellular response to thyroid hormone stimulus : IEA:Ensembl
  • collagen catabolic process : ISO:MGI
  • decidualization : IGI:MGI
  • epithelial cell differentiation : IEA:Ensembl
  • negative regulation of cell death : ISO:MGI
  • proteolysis : ISO:MGI
  • proteolysis involved in cellular protein catabolic process : ISO:MGI
  • regulation of catalytic activity : IEA:InterPro
  • viral entry into host cell : IMP:CACAO
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.