| Signal peptide(a) |
N |
Secretome P(b) |
0.723 |
| Function |
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity. . |
| GO - Molecular function |
- cytokine activity : IEA:UniProtKB-KW
- extracellular matrix binding : IBA:GO_Central
- integrin binding : IPI:ARUK-UCL
|
| GO - Biological process |
- androgen catabolic process : IDA:CAFA
- biomineral tissue development : IEA:UniProtKB-KW
- cell adhesion : IDA:ARUK-UCL
- cellular protein metabolic process : TAS:Reactome
- cellular response to testosterone stimulus : IDA:CAFA
- decidualization : TAS:BHF-UCL
- embryo implantation : TAS:BHF-UCL
- extracellular matrix organization : TAS:Reactome
- inflammatory response : IEA:Ensembl
- negative regulation of collateral sprouting of intact axon in response to injury : IEA:Ensembl
- osteoblast differentiation : IBA:GO_Central
- positive regulation of bone resorption : IBA:GO_Central
- positive regulation of estradiol secretion : IDA:CAFA
- positive regulation of transcription, DNA-templated : IDA:CAFA
- post-translational protein modification : TAS:Reactome
- response to steroid hormone : IEA:Ensembl
- response to vitamin D : IDA:BHF-UCL
|