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P10155

60 kDa SS-A/Ro ribonucleoprotein (P10155)

Uniprot ID P10155
Protein Name 60 kDa SS-A/Ro ribonucleoprotein
Gene Name TROVE2
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.506
Function RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation. .May play roles in cilia formation and/or maintenance. {ECO:0000250}.
GO - Molecular function
  • metal ion binding : IEA:UniProtKB-KW
  • RNA binding : TAS:ProtInc
  • U2 snRNA binding : IEA:Ensembl
GO - Biological process
  • cilium assembly : IEA:Ensembl
  • immune system development : IEA:Ensembl
  • response to UV : IEA:Ensembl
  • smoothened signaling pathway : IEA:Ensembl
  • transcription by RNA polymerase III : TAS:ProtInc
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.