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P09602

Non-histone chromosomal protein HMG-17 (P09602)

Uniprot ID P09602
Protein Name Non-histone chromosomal protein HMG-17
Gene Name Hmgn2
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.825
Function Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity). .
GO - Molecular function
  • nucleosomal DNA binding : IEA:InterPro
GO - Biological process
  • negative regulation of transcription by RNA polymerase II : IMP:MGI
  • regulation of development, heterochronic : IGI:MGI
  • regulation of transcription by RNA polymerase II : IMP:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.