Stromelysin-2 (P09238)

Uniprot ID P09238
Protein Name Stromelysin-2
Gene Name MMP10
Species Homo sapiens (Human)
Signal peptide(a) Y Secretome P(b) 0.515
Function Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.
GO - Molecular function
  • metalloendopeptidase activity : IBA:GO_Central
  • zinc ion binding : TAS:ProtInc
GO - Biological process
  • collagen catabolic process : IBA:GO_Central
  • extracellular matrix disassembly : TAS:Reactome
  • extracellular matrix organization : IBA:GO_Central
  • proteolysis : TAS:ProtInc
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.