Transthyretin (P07309)

Uniprot ID P07309
Protein Name Transthyretin
Gene Name Ttr
Species Mus musculus (Mouse)
Signal peptide(a) Y Secretome P(b) 0.648
Function Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
GO - Molecular function
  • hormone activity : IEA:UniProtKB-KW
  • hormone binding : ISO:MGI
  • identical protein binding : ISO:MGI
  • protein heterodimerization activity : ISO:MGI
  • thyroid hormone binding : IBA:GO_Central
GO - Biological process
  • retinol metabolic process : IEA:InterPro
  • thyroid hormone transport : IEA:InterPro
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.