Signal peptide(a) |
Y |
Secretome P(b) |
0.438 |
Function |
Factor H functions as a cofactor in the inactivation of C3b by factor I and also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b)NBB complex (C5 convertase) in the alternative complement pathway. . |
GO - Molecular function |
- complement component C3b binding : IPI:MGI
- heparan sulfate proteoglycan binding : ISO:MGI
- heparin binding : IDA:MGI
|
GO - Biological process |
- complement activation : ISO:MGI
- complement activation, alternative pathway : IEA:UniProtKB-KW
- positive regulation of cytolysis : IDA:UniProtKB
- regulation of complement activation : IMP:MGI
|