Myelin protein P0 (P06907)

Uniprot ID P06907
Protein Name Myelin protein P0
Gene Name Mpz
Species Rattus norvegicus (Rat)
Signal peptide(a) Y Secretome P(b)
Function Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction. .
GO - Molecular function
GO - Biological process
  • cell aggregation : ISS:UniProtKB
  • cell-cell adhesion via plasma-membrane adhesion molecules : ISS:UniProtKB
  • cell-cell junction maintenance : ISO:RGD
  • myelination : ISS:UniProtKB
  • negative regulation of apoptotic process : IMP:RGD
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.