Cathepsin L1 (P06797)

Uniprot ID P06797
Protein Name Cathepsin L1
Gene Name Ctsl
Species Mus musculus (Mouse)
Signal peptide(a) Y Secretome P(b) 0.621
Function Important for the overall degradation of proteins in lysosomes.
GO - Molecular function
  • aminopeptidase activity : ISS:BHF-UCL
  • cysteine-type carboxypeptidase activity : IDA:MGI
  • cysteine-type endopeptidase activity : ISS:BHF-UCL
  • histone binding : IDA:BHF-UCL
  • kininogen binding : ISO:MGI
  • peptide binding : ISS:BHF-UCL
  • protein-containing complex binding : ISO:MGI
GO - Biological process
  • autophagic cell death : ISS:BHF-UCL
  • cell communication : ISS:BHF-UCL
  • cellular response to starvation : ISS:BHF-UCL
  • decidualization : IGI:MGI
  • hair follicle morphogenesis : IMP:MGI
  • male gonad development : ISS:BHF-UCL
  • multicellular organism aging : ISS:BHF-UCL
  • negative regulation of keratinocyte proliferation : IMP:MGI
  • nerve development : ISS:BHF-UCL
  • protein autoprocessing : IDA:MGI
  • protein processing : IDA:MGI
  • proteolysis : IDA:BHF-UCL
  • proteolysis involved in cellular protein catabolic process : IBA:GO_Central
  • regulation of actin cytoskeleton reorganization : IGI:MGI
  • response to glucocorticoid : ISS:BHF-UCL
  • response to glucose : ISS:BHF-UCL
  • response to gonadotropin : ISS:BHF-UCL
  • response to odorant : IEA:Ensembl
  • response to organic cyclic compound : ISS:BHF-UCL
  • Sertoli cell differentiation : ISS:BHF-UCL
  • spermatogenesis : ISS:BHF-UCL
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.