| Signal peptide(a) |
N |
Secretome P(b) |
0.576 |
| Function |
Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. |
| GO - Molecular function |
- cytokine activity : IEA:UniProtKB-KW
- glucose-6-phosphate isomerase activity : IDA:MGI
- growth factor activity : IEA:UniProtKB-KW
- intramolecular transferase activity : ISO:MGI
- monosaccharide binding : ISO:MGI
- ubiquitin protein ligase binding : ISO:MGI
|
| GO - Biological process |
- aldehyde catabolic process : ISO:MGI
- carbohydrate metabolic process : ISO:MGI
- erythrocyte homeostasis : IMP:MGI
- gluconeogenesis : IEA:UniProtKB-KW
- glucose 6-phosphate metabolic process : ISO:MGI
- glucose homeostasis : IMP:MGI
- glycolytic process : IDA:MGI
- glycolytic process through glucose-6-phosphate : IC:MGI
- in utero embryonic development : IMP:MGI
- learning or memory : IEA:Ensembl
- mesoderm formation : IMP:MGI
- methylglyoxal biosynthetic process : ISO:MGI
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process : ISO:MGI
- negative regulation of neuron apoptotic process : ISO:MGI
- positive regulation of immunoglobulin secretion : ISO:MGI
- response to cadmium ion : IEA:Ensembl
- response to estradiol : IEA:Ensembl
- response to immobilization stress : IEA:Ensembl
- response to morphine : ISO:MGI
- response to muscle stretch : IEA:Ensembl
- response to progesterone : IEA:Ensembl
- response to testosterone : IEA:Ensembl
|