Prothymosin alpha (P06302)

Uniprot ID P06302
Protein Name Prothymosin alpha
Gene Name Ptma
Species Rattus norvegicus (Rat)
Signal peptide(a) N Secretome P(b)
Function Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
GO - Molecular function
  • activating transcription factor binding : ISO:RGD
  • histone binding : ISO:RGD
GO - Biological process
  • cell differentiation : TAS:RGD
  • cell population proliferation : TAS:RGD
  • histone exchange : ISO:RGD
  • negative regulation of apoptotic process : IDA:RGD
  • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process : IDA:RGD
  • positive regulation of NF-kappaB transcription factor activity : IGI:CAFA
  • positive regulation of transcription by RNA polymerase II : IDA:RGD
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.