Tetranectin (P05452)

Uniprot ID P05452
Protein Name Tetranectin
Gene Name CLEC3B
Species Homo sapiens (Human)
Signal peptide(a) Y Secretome P(b) 0.653
Function Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.
GO - Molecular function
  • calcium ion binding : IDA:UniProtKB
  • carbohydrate binding : IEA:UniProtKB-KW
  • heparin binding : IDA:UniProtKB
  • kringle domain binding : IPI:UniProtKB
GO - Biological process
  • bone mineralization : IDA:UniProtKB
  • cellular response to organic substance : IEP:UniProtKB
  • cellular response to transforming growth factor beta stimulus : IEP:UniProtKB
  • ossification : IEP:UniProtKB
  • platelet degranulation : TAS:Reactome
  • positive regulation of plasminogen activation : ISS:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.