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P05413

Fatty acid-binding protein, heart (P05413)

Uniprot ID P05413
Protein Name Fatty acid-binding protein, heart
Gene Name FABP3
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.813
Function FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
GO - Molecular function
  • cytoskeletal protein binding : IPI:UniProtKB
  • icosatetraenoic acid binding : IEA:Ensembl
  • long-chain fatty acid binding : IDA:BHF-UCL
  • long-chain fatty acid transporter activity : IEA:Ensembl
  • oleic acid binding : IDA:BHF-UCL
GO - Biological process
  • cholesterol homeostasis : ISS:BHF-UCL
  • fatty acid metabolic process : IEA:Ensembl
  • long-chain fatty acid import : ISS:BHF-UCL
  • negative regulation of cell proliferation : TAS:ProtInc
  • phospholipid homeostasis : ISS:BHF-UCL
  • positive regulation of phospholipid biosynthetic process : IC:BHF-UCL
  • regulation of fatty acid oxidation : ISS:BHF-UCL
  • regulation of phosphatidylcholine biosynthetic process : IEA:Ensembl
  • response to drug : IEA:Ensembl
  • response to fatty acid : IEA:Ensembl
  • response to insulin : IEA:Ensembl
  • triglyceride catabolic process : TAS:Reactome
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.