Signal peptide(a) |
N |
Secretome P(b) |
0.639 |
Function |
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids. . |
GO - Molecular function |
- amino acid binding : ISO:MGI
- carboxylic acid binding : ISO:MGI
- enzyme binding : ISO:MGI
- kynurenine-oxoglutarate transaminase activity : IEA:UniProtKB-EC
- L-aspartate : IDA:MGI
- phospholipid binding : ISO:MGI
- protein homodimerization activity : ISO:MGI
- pyridoxal phosphate binding : ISO:MGI
|
GO - Biological process |
- 2-oxoglutarate metabolic process : ISS:UniProtKB
- aspartate biosynthetic process : IDA:MGI
- aspartate catabolic process : ISO:MGI
- aspartate metabolic process : ISS:UniProtKB
- cellular amino acid metabolic process : ISO:MGI
- dicarboxylic acid metabolic process : ISO:MGI
- fatty acid transport : IEA:Ensembl
- female pregnancy : IEA:Ensembl
- glutamate catabolic process to 2-oxoglutarate : IDA:MGI
- glutamate catabolic process to aspartate : IDA:MGI
- glutamate metabolic process : ISS:UniProtKB
- lactation : IEA:Ensembl
- oxaloacetate metabolic process : IDA:MGI
- response to ethanol : ISO:MGI
- response to insulin : IEA:Ensembl
- response to morphine : IEA:Ensembl
- response to muscle activity : IEA:Ensembl
|