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P05065

Fructose-bisphosphate aldolase A (P05065)

Uniprot ID P05065
Protein Name Fructose-bisphosphate aldolase A
Gene Name Aldoa
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity). .
GO - Molecular function
  • cytoskeletal protein binding : ISO:RGD
  • fructose binding : ISO:RGD
  • fructose-bisphosphate aldolase activity : ISS:UniProtKB
  • identical protein binding : ISO:RGD
  • protease binding : ISO:RGD
GO - Biological process
  • ATP biosynthetic process : ISO:RGD
  • binding of sperm to zona pellucida : ISO:RGD
  • fructose 1,6-bisphosphate metabolic process : ISO:RGD
  • fructose metabolic process : ISO:RGD
  • glycolytic process : ISS:UniProtKB
  • methylglyoxal biosynthetic process : IMP:RGD
  • muscle cell cellular homeostasis : ISO:RGD
  • positive regulation of cell migration : ISO:RGD
  • protein homotetramerization : ISS:UniProtKB
  • regulation of cell shape : ISO:RGD
  • response to estrogen : IEP:RGD
  • response to heat : IEP:RGD
  • response to hypoxia : IEP:RGD
  • response to lipopolysaccharide : IEP:RGD
  • response to nicotine : IEP:RGD
  • striated muscle contraction : ISO:RGD
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.