Glutathione S-transferase Mu 1 (P04905)

Uniprot ID P04905
Protein Name Glutathione S-transferase Mu 1
Gene Name Gstm1
Species Rattus norvegicus (Rat)
Signal peptide(a) N Secretome P(b)
Function Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. The olfactory GST may be crucial for the acuity of the olfactory process.
GO - Molecular function
  • enzyme binding : ISO:RGD
  • glutathione binding : IDA:CAFA
  • glutathione transferase activity : IDA:CAFA
  • identical protein binding : IPI:RGD
  • nickel cation binding : IDA:RGD
  • protein heterodimerization activity : ISO:RGD
  • protein homodimerization activity : ISO:RGD
  • protein kinase binding : IPI:RGD
  • steroid binding : IPI:RGD
GO - Biological process
  • aging : IEP:RGD
  • cellular detoxification of nitrogen compound : ISO:RGD
  • cellular response to drug : ISO:RGD
  • glutathione metabolic process : IDA:UniProtKB
  • nitrobenzene metabolic process : ISO:RGD
  • response to amino acid : IEP:RGD
  • response to antibiotic : IEP:RGD
  • response to axon injury : IEP:RGD
  • response to drug : IEP:RGD
  • response to ethanol : IEP:RGD
  • response to lead ion : IEP:RGD
  • response to lithium ion : IEP:RGD
  • response to metal ion : IEP:RGD
  • sensory perception of smell : IEA:UniProtKB-KW
  • xenobiotic catabolic process : IDA:CAFA
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.