| Signal peptide(a) |
Y |
Secretome P(b) |
0.868 |
| Function |
Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. . |
| GO - Molecular function |
- cytokine activity : IDA:UniProtKB
- granulocyte macrophage colony-stimulating factor receptor binding : TAS:ProtInc
- growth factor activity : IEA:UniProtKB-KW
- protein tyrosine kinase activity : TAS:Reactome
- Ras guanyl-nucleotide exchange factor activity : TAS:Reactome
|
| GO - Biological process |
- cellular response to granulocyte macrophage colony-stimulating factor stimulus : IDA:CAFA
- cellular response to lipopolysaccharide : IEA:Ensembl
- cytokine-mediated signaling pathway : TAS:Reactome
- dendritic cell differentiation : IDA:DFLAT
- embryonic placenta development : IEA:Ensembl
- epithelial fluid transport : IEA:Ensembl
- histamine secretion : IEA:Ensembl
- immune response : IEA:InterPro
- macrophage activation : IEA:Ensembl
- MAPK cascade : TAS:Reactome
- monocyte differentiation : IEA:Ensembl
- myeloid dendritic cell differentiation : IDA:UniProtKB
- negative regulation of cytolysis : IDA:BHF-UCL
- negative regulation of extrinsic apoptotic signaling pathway in absence of ligand : IDA:BHF-UCL
- negative regulation of transcription, DNA-templated : IDA:UniProtKB
- neutrophil differentiation : IEA:Ensembl
- positive regulation of cell proliferation : IDA:BHF-UCL
- positive regulation of gene expression : IDA:BHF-UCL
- positive regulation of interleukin-23 production : IDA:BHF-UCL
- positive regulation of macrophage derived foam cell differentiation : IDA:BHF-UCL
- positive regulation of podosome assembly : IDA:BHF-UCL
- positive regulation of tyrosine phosphorylation of STAT protein : IDA:BHF-UCL
- regulation of circadian sleep/wake cycle, sleep : IEA:Ensembl
- regulation of myeloid cell differentiation : TAS:Reactome
- response to fluid shear stress : IEA:Ensembl
- response to silicon dioxide : IEA:Ensembl
|