Fatty acid-binding protein, adipocyte (P04117)

Uniprot ID P04117
Protein Name Fatty acid-binding protein, adipocyte
Gene Name Fabp4
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.883
Function Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. .
GO - Molecular function
  • fatty acid binding : IEA:InterPro
GO - Biological process
  • brown fat cell differentiation : IDA:MGI
  • cellular response to lithium ion : IDA:MGI
  • cellular response to tumor necrosis factor : IDA:MGI
  • cholesterol homeostasis : IMP:MGI
  • cytokine production : IMP:MGI
  • fatty acid metabolic process : ISO:MGI
  • negative regulation of protein kinase activity : IMP:MGI
  • negative regulation of transcription, DNA-templated : IMP:MGI
  • positive regulation of cell proliferation : ISO:MGI
  • positive regulation of inflammatory response : IMP:MGI
  • white fat cell differentiation : IDA:MGI
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.