Laminin subunit gamma-1 (P02468)

Uniprot ID P02468
Protein Name Laminin subunit gamma-1
Gene Name Lamc1
Species Mus musculus (Mouse)
Signal peptide(a) Y Secretome P(b) 0.0
Function Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
GO - Molecular function
  • extracellular matrix structural constituent : ISS:HGNC
  • glycosphingolipid binding : IDA:MGI
GO - Biological process
  • cell adhesion : ISS:HGNC
  • cell migration : ISS:HGNC
  • extracellular matrix disassembly : ISS:HGNC
  • hemidesmosome assembly : ISS:HGNC
  • neuron projection development : IDA:MGI
  • protein-containing complex assembly : ISS:HGNC
  • substrate adhesion-dependent cell spreading : ISO:MGI
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.