| Signal peptide(a) |
Y |
Secretome P(b) |
0.242 |
| Function |
Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12. |
| GO - Molecular function |
- extracellular matrix structural constituent : IMP:UniProtKB
- integrin binding : IMP:UniProtKB
- metal ion binding : IEA:UniProtKB-KW
- platelet-derived growth factor binding : IDA:MGI
- protease binding : IPI:CAFA
- SMAD binding : IEA:Ensembl
|
| GO - Biological process |
- aging : IEA:Ensembl
- aorta smooth muscle tissue morphogenesis : IEA:Ensembl
- cell-matrix adhesion : IDA:UniProtKB
- cellular response to amino acid stimulus : IEA:Ensembl
- cerebral cortex development : ISS:UniProtKB
- collagen fibril organization : IMP:UniProtKB
- digestive tract development : IEA:Ensembl
- extracellular matrix organization : TAS:Reactome
- heart development : IMP:UniProtKB
- integrin-mediated signaling pathway : IMP:UniProtKB
- negative regulation of immune response : IMP:UniProtKB
- negative regulation of neuron migration : ISS:UniProtKB
- peptide cross-linking : IDA:UniProtKB
- platelet activation : NAS:UniProtKB
- positive regulation of Rho protein signal transduction : ISS:UniProtKB
- regulation of immune response : TAS:Reactome
- response to cytokine : IDA:UniProtKB
- response to mechanical stimulus : IEA:Ensembl
- response to radiation : IDA:UniProtKB
- skeletal system development : IEA:Ensembl
- skin development : IMP:UniProtKB
- supramolecular fiber organization : IMP:UniProtKB
- transforming growth factor beta receptor signaling pathway : IDA:UniProtKB
- wound healing : IDA:UniProtKB
|