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P02091

Hemoglobin subunit beta-1 (P02091)

Uniprot ID P02091
Protein Name Hemoglobin subunit beta-1
Gene Name Hbb
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (2) Interactions
Signal peptide(a) N Secretome P(b)
Function Involved in oxygen transport from the lung to the various peripheral tissues.
GO - Molecular function
  • heme binding : IBA:GO_Central
  • hemoglobin alpha binding : IDA:RGD
  • hemoglobin beta binding : IDA:RGD
  • hemoglobin binding : ISO:RGD
  • metal ion binding : IEA:UniProtKB-KW
  • organic acid binding : IBA:GO_Central
  • oxygen binding : ISO:RGD
  • oxygen carrier activity : ISO:RGD
  • protein-containing complex binding : IDA:RGD
GO - Biological process
  • cellular oxidant detoxification : IEA:GOC
  • erythrocyte development : ISO:RGD
  • glutathione metabolic process : IDA:RGD
  • hemopoiesis : ISO:RGD
  • hydrogen peroxide catabolic process : ISO:RGD
  • oxygen transport : IDA:RGD
  • positive regulation of cell death : ISO:RGD
  • regulation of eIF2 alpha phosphorylation by heme : ISO:RGD
  • renal absorption : ISO:RGD
  • response to hydrogen peroxide : ISO:RGD
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.