H-2 class I histocompatibility antigen, D-B alpha chain (P01899)

Uniprot ID P01899
Protein Name H-2 class I histocompatibility antigen, D-B alpha chain
Gene Name H2-D1
Species Mus musculus (Mouse)
Signal peptide(a) Y Secretome P(b) 0.341
Function Involved in the presentation of foreign antigens to the immune system.
GO - Molecular function
  • beta-2-microglobulin binding : ISO:MGI
  • peptide antigen binding : ISO:MGI
  • peptide binding : ISO:MGI
  • protein heterodimerization activity : ISO:MGI
  • signaling receptor binding : ISO:MGI
  • T cell receptor binding : ISO:MGI
  • TAP binding : ISO:MGI
GO - Biological process
  • antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent : IDA:MGI
  • immune response : IEA:InterPro
  • negative regulation of neuron projection development : IDA:MGI
  • positive regulation of T cell mediated cytotoxicity : IDA:MGI
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.