| Signal peptide(a) |
Y |
Secretome P(b) |
0.924 |
| Function |
As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. |
| GO - Molecular function |
- amyloid-beta binding : IPI:BHF-UCL
- cysteine-type endopeptidase inhibitor activity : IDA:UniProtKB
- endopeptidase inhibitor activity : IDA:UniProtKB
- identical protein binding : IPI:IntAct
- protease binding : IPI:BHF-UCL
|
| GO - Biological process |
- apoptotic process : IEA:Ensembl
- brain development : IEA:Ensembl
- cellular protein metabolic process : TAS:Reactome
- cellular response to hydrogen peroxide : IEA:Ensembl
- circadian sleep/wake cycle, REM sleep : IEA:Ensembl
- defense response : IDA:BHF-UCL
- embryo implantation : IEA:Ensembl
- eye development : IEA:Ensembl
- negative regulation of blood vessel remodeling : IEP:BHF-UCL
- negative regulation of cell death : IEA:Ensembl
- negative regulation of collagen catabolic process : IEP:BHF-UCL
- negative regulation of cysteine-type endopeptidase activity : IBA:GO_Central
- negative regulation of elastin catabolic process : IMP:BHF-UCL
- negative regulation of extracellular matrix disassembly : IEP:BHF-UCL
- negative regulation of peptidase activity : IDA:BHF-UCL
- negative regulation of proteolysis : IDA:UniProtKB
- neutrophil degranulation : TAS:Reactome
- positive regulation of cell proliferation : IEA:Ensembl
- positive regulation of DNA replication : IEA:Ensembl
- post-translational protein modification : TAS:Reactome
- regulation of programmed cell death : IEA:Ensembl
- regulation of tissue remodeling : IEP:BHF-UCL
- response to axon injury : IEA:Ensembl
- response to carbohydrate : IEA:Ensembl
- response to estradiol : IEA:Ensembl
- response to hypoxia : IEA:Ensembl
- response to nutrient levels : IEA:Ensembl
- salivary gland development : IEA:Ensembl
- Sertoli cell development : IEA:Ensembl
- supramolecular fiber organization : IGI:BHF-UCL
|