Signal peptide(a) |
Y |
Secretome P(b) |
0.393 |
Function |
Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. Catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens (By similarity). . |
GO - Molecular function |
- carbohydrate binding : ISO:MGI
- complement binding : ISO:MGI
- complement component C1q binding : ISO:MGI
- endopeptidase inhibitor activity : IEA:InterPro
|
GO - Biological process |
- complement activation : IMP:MGI
- complement activation, classical pathway : IEA:UniProtKB-KW
- immunoglobulin mediated immune response : IMP:MGI
- inflammatory response : IEA:UniProtKB-KW
- innate immune response : IEA:UniProtKB-KW
|