| Signal peptide(a) |
N |
Secretome P(b) |
0.797 |
| Function |
Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. . |
| GO - Molecular function |
- arylesterase activity : ISO:MGI
- carbonate dehydratase activity : IDA:MGI
- zinc ion binding : ISO:MGI
|
| GO - Biological process |
- angiotensin-activated signaling pathway : ISS:UniProtKB
- carbon dioxide transport : IMP:MGI
- cellular response to fluid shear stress : IEA:Ensembl
- kidney development : IEA:Ensembl
- morphogenesis of an epithelium : IMP:MGI
- odontogenesis of dentin-containing tooth : IEA:Ensembl
- positive regulation of bone resorption : ISO:MGI
- positive regulation of cellular pH reduction : IMP:MGI
- positive regulation of dipeptide transmembrane transport : IMP:UniProtKB
- positive regulation of osteoclast differentiation : ISO:MGI
- positive regulation of synaptic transmission, GABAergic : IGI:MGI
- regulation of anion transport : ISS:UniProtKB
- regulation of chloride transport : IMP:MGI
- regulation of intracellular pH : IMP:UniProtKB
- regulation of pH : IC:MGI
- response to estrogen : IEA:Ensembl
- response to pH : IEA:Ensembl
- response to steroid hormone : IEA:Ensembl
- response to zinc ion : IEA:Ensembl
- secretion : IMP:MGI
|