| Signal peptide(a) |
Y |
Secretome P(b) |
|
| Function |
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (PubMed:1639824). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). . |
| GO - Molecular function |
- collagen binding : ISO:RGD
- cysteine-type endopeptidase activity : IDA:CAFA
- cysteine-type peptidase activity : ISO:RGD
- endopeptidase activity : IDA:RGD
- kininogen binding : IPI:RGD
- peptidase activity : ISO:RGD
- peptide binding : IDA:RGD
- protein self-association : IDA:RGD
- protein-containing complex binding : IPI:RGD
- proteoglycan binding : ISO:RGD
|
| GO - Biological process |
- autophagy : IEP:RGD
- cellular response to mechanical stimulus : IEP:RGD
- cellular response to thyroid hormone stimulus : ISO:RGD
- collagen catabolic process : ISO:RGD
- decidualization : ISO:RGD
- epithelial cell differentiation : ISO:RGD
- negative regulation of cell death : IMP:RGD
- proteolysis : IDA:CAFA
- proteolysis involved in cellular protein catabolic process : ISO:RGD
- regulation of catalytic activity : IEA:InterPro
- response to amine : IEP:RGD
- response to cytokine : IEP:RGD
- response to ethanol : IEP:RGD
- response to glucose : IEP:RGD
- response to interleukin-4 : IEP:RGD
- response to mechanical stimulus : IEP:RGD
- response to organic cyclic compound : IEP:RGD
- response to peptide hormone : IEP:RGD
- response to wounding : IEP:RGD
- skeletal muscle tissue development : IEP:RGD
- spermatogenesis : IEP:RGD
- viral entry into host cell : ISO:RGD
|