Uniprot ID | P00750 | ||
Protein Name | Tissue-type plasminogen activator | ||
Gene Name | PLAT | ||
Species | Homo sapiens (Human) |
Signal peptide(a) | Y | Secretome P(b) | 0.638 |
Function | Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration. | ||
GO - Molecular function |
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GO - Biological process |
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