Ribonuclease pancreatic (P00683)

Uniprot ID P00683
Protein Name Ribonuclease pancreatic
Gene Name Rnase1
Species Mus musculus (Mouse)
Signal peptide(a) Y Secretome P(b) 0.0
Function Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA (By similarity). .
GO - Molecular function
  • endonuclease activity : IBA:GO_Central
  • nucleic acid binding : IEA:InterPro
  • ribonuclease A activity : IEA:UniProtKB-EC
  • ribonuclease activity : ISO:MGI
GO - Biological process
  • RNA phosphodiester bond hydrolysis : ISO:MGI
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.