Ribonuclease pancreatic (P00683)

Uniprot ID	P00683
Protein Name	Ribonuclease pancreatic
Gene Name	Rnase1
Species	Mus musculus (Mouse)

Signal peptide^(a)	Y	Secretome P^(b)	0.0
Function	Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA (By similarity). .
GO - Molecular function	endonuclease activity : IBA:GO_Central nucleic acid binding : IEA:InterPro ribonuclease A activity : IEA:UniProtKB-EC ribonuclease activity : ISO:MGI
GO - Biological process	RNA phosphodiester bond hydrolysis : ISO:MGI

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^{(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.}
^{(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.}