G2/mitotic-specific cyclin-B2 (O95067)

Uniprot ID O95067
Protein Name G2/mitotic-specific cyclin-B2
Gene Name CCNB2
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b)
Function Essential for the control of the cell cycle at the G2/M (mitosis) transition.
GO - Molecular function
  • cadherin binding : HDA:BHF-UCL
  • cyclin-dependent protein serine/threonine kinase regulator activity : IBA:GO_Central
  • protein kinase binding : IBA:GO_Central
GO - Biological process
  • cell division : IEA:UniProtKB-KW
  • G2/M transition of mitotic cell cycle : TAS:Reactome
  • in utero embryonic development : IEA:Ensembl
  • mitotic cell cycle phase transition : IBA:GO_Central
  • mitotic nuclear envelope disassembly : TAS:Reactome
  • protein phosphorylation : IEA:GOC
  • regulation of cell cycle : TAS:Reactome
  • regulation of cyclin-dependent protein serine/threonine kinase activity : IBA:GO_Central
  • regulation of growth : IEA:Ensembl
  • T cell homeostasis : IEA:Ensembl
  • thymus development : IEA:Ensembl
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.