Signal peptide(a) |
Y |
Secretome P(b) |
0.588 |
Function |
Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L. |
GO - Molecular function |
- collagen binding : ISO:MGI
- cysteine-type endopeptidase activity : EXP:Reactome
- cysteine-type peptidase activity : ISO:MGI
- fibronectin binding : ISO:MGI
- laminin binding : ISO:MGI
- peptidase activity : IDA:MGI
- proteoglycan binding : ISO:MGI
|
GO - Biological process |
- antigen processing and presentation : IBA:GO_Central
- antigen processing and presentation of peptide antigen : ISO:MGI
- basement membrane disassembly : IMP:BHF-UCL
- bone resorption : ISO:MGI
- collagen catabolic process : ISO:MGI
- immune response : IBA:GO_Central
- positive regulation of cation channel activity : IDA:CACAO
- positive regulation of inflammatory response : IGI:MGI
- protein processing : ISO:MGI
- proteolysis : IDA:MGI
- proteolysis involved in cellular protein catabolic process : IMP:BHF-UCL
- regulation of sensory perception of pain : ISO:MGI
- response to acidic pH : ISO:MGI
|