SPI6 (O08797)

Uniprot ID O08797
Protein Name SPI6
Gene Name Serpinb9
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.675
GO - Molecular function
  • cysteine-type endopeptidase inhibitor activity involved in apoptotic process : ISO:MGI
  • protease binding : ISO:MGI
  • serine-type endopeptidase inhibitor activity : IMP:MGI
GO - Biological process
  • acute inflammatory response to antigenic stimulus : IMP:MGI
  • defense response to bacterium : IMP:MGI
  • immune response : ISO:MGI
  • negative regulation by symbiont of host apoptotic process : ISO:MGI
  • negative regulation of apoptotic process : IDA:MGI
  • negative regulation of endopeptidase activity : ISO:MGI
  • negative regulation of T cell apoptotic process : IMP:MGI
  • positive regulation of gene expression : ISO:MGI
  • protection from natural killer cell mediated cytotoxicity : ISO:MGI
  • response to bacterium : ISO:MGI
  • T cell mediated cytotoxicity : IMP:MGI
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.