Signal peptide(a) |
N |
Secretome P(b) |
0.612 |
Function |
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis. . |
GO - Molecular function |
- hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds : IEA:InterPro
- identical protein binding : ISO:MGI
- microtubule binding : IEA:InterPro
- protein kinase binding : IPI:UniProtKB
|
GO - Biological process |
- axon guidance : IEA:InterPro
- cytoskeleton organization : IDA:UniProtKB
- endocytosis : ISS:UniProtKB
- olfactory bulb development : IEA:Ensembl
- positive regulation of glutamate secretion : ISO:MGI
- regulation of axon extension : IEA:InterPro
- regulation of neuron differentiation : ISO:MGI
- regulation of neuron projection development : IGI:MGI
- response to amphetamine : IEA:Ensembl
- response to cocaine : IEA:Ensembl
- spinal cord development : IEA:Ensembl
- synaptic vesicle transport : ISO:MGI
|