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M3Z3F9

Secreted frizzled related protein 4 (M3Z3F9)

Uniprot ID M3Z3F9
Protein Name Secreted frizzled related protein 4
Gene Name SFRP4
Species Mustela putorius furo (European domestic ferret) (Mustela furo)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.601
Function
GO - Molecular function
  • Wnt-protein binding : IEA:Ensembl
GO - Biological process
  • bone morphogenesis : IEA:Ensembl
  • negative regulation of canonical Wnt signaling pathway : IEA:Ensembl
  • negative regulation of cell proliferation : IEA:Ensembl
  • negative regulation of DNA binding transcription factor activity : IEA:Ensembl
  • negative regulation of non-canonical Wnt signaling pathway : IEA:Ensembl
  • negative regulation of sodium-dependent phosphate transport : IEA:Ensembl
  • phosphate ion homeostasis : IEA:Ensembl
  • positive regulation of canonical Wnt signaling pathway : IEA:Ensembl
  • positive regulation of epidermal cell differentiation : IEA:Ensembl
  • positive regulation of gene expression : IEA:Ensembl
  • positive regulation of keratinocyte apoptotic process : IEA:Ensembl
  • positive regulation of receptor internalization : IEA:Ensembl
  • regulation of BMP signaling pathway : IEA:Ensembl
  • Wnt signaling pathway : IEA:UniProtKB-KW
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.