Serpin family E member 2 (M3YZ28)

Uniprot ID M3YZ28
Protein Name Serpin family E member 2
Gene Name SERPINE2
Species Mustela putorius furo (European domestic ferret) (Mustela furo)
Signal peptide(a) N Secretome P(b) 0.529
Function
GO - Molecular function
  • heparin binding : IEA:Ensembl
  • serine-type endopeptidase inhibitor activity : IEA:Ensembl
  • signaling receptor binding : IEA:Ensembl
GO - Biological process
  • blood coagulation : IEA:Ensembl
  • cerebellar granular layer morphogenesis : IEA:Ensembl
  • detection of mechanical stimulus involved in sensory perception : IEA:Ensembl
  • innervation : IEA:Ensembl
  • long-term synaptic potentiation : IEA:Ensembl
  • mating plug formation : IEA:Ensembl
  • negative regulation of cell growth : IEA:Ensembl
  • negative regulation of cell proliferation : IEA:Ensembl
  • negative regulation of phosphatidylinositol 3-kinase signaling : IEA:Ensembl
  • negative regulation of plasminogen activation : IEA:Ensembl
  • negative regulation of platelet aggregation : IEA:Ensembl
  • negative regulation of protein catabolic process : IEA:Ensembl
  • negative regulation of smoothened signaling pathway : IEA:Ensembl
  • negative regulation of sodium ion transport : IEA:Ensembl
  • positive regulation of astrocyte differentiation : IEA:Ensembl
  • regulation of synaptic transmission, glutamatergic : IEA:Ensembl
  • regulation of timing of cell differentiation : IEA:Ensembl
  • secretion by cell : IEA:Ensembl
  • secretory granule organization : IEA:Ensembl
  • seminal vesicle epithelium development : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.