Insulin like growth factor binding protein 4 (M3YTA9)

Uniprot ID M3YTA9
Protein Name Insulin like growth factor binding protein 4
Gene Name IGFBP4
Species Mustela putorius furo (European domestic ferret) (Mustela furo)
Signal peptide(a) Y Secretome P(b) 0.878
Function
GO - Molecular function
  • insulin-like growth factor binding : IEA:Ensembl
GO - Biological process
  • positive regulation of insulin-like growth factor receptor signaling pathway : IEA:Ensembl
  • positive regulation of MAPK cascade : IEA:Ensembl
  • regulation of cell growth : IEA:Ensembl
  • regulation of glucose metabolic process : IEA:Ensembl
  • type B pancreatic cell proliferation : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.