TIMP metallopeptidase inhibitor 1 (M3YPK1)

Uniprot ID M3YPK1
Protein Name TIMP metallopeptidase inhibitor 1
Gene Name TIMP1
Species Mustela putorius furo (European domestic ferret) (Mustela furo)
Signal peptide(a) Y Secretome P(b) 0.869
Function
GO - Molecular function
  • cytokine activity : IEA:Ensembl
  • metalloendopeptidase inhibitor activity : IEA:Ensembl
  • zinc ion binding : IEA:Ensembl
GO - Biological process
  • connective tissue replacement involved in inflammatory response wound healing : IEA:Ensembl
  • negative regulation of membrane protein ectodomain proteolysis : IEA:Ensembl
  • negative regulation of metallopeptidase activity : IEA:Ensembl
  • negative regulation of trophoblast cell migration : IEA:Ensembl
  • positive regulation of cell proliferation : IEA:Ensembl
  • regulation of integrin-mediated signaling pathway : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.