Fibrillin 1 (M3YKB1)

Uniprot ID M3YKB1
Protein Name Fibrillin 1
Gene Name FBN1
Species Mustela putorius furo (European domestic ferret) (Mustela furo)
Signal peptide(a) Y Secretome P(b) 0.476
Function
GO - Molecular function
  • calcium ion binding : IEA:Ensembl
  • extracellular matrix structural constituent : IEA:Ensembl
  • heparin binding : IEA:Ensembl
  • identical protein binding : IEA:Ensembl
  • integrin binding : IEA:Ensembl
GO - Biological process
  • camera-type eye development : IEA:Ensembl
  • cell adhesion mediated by integrin : IEA:Ensembl
  • embryonic eye morphogenesis : IEA:Ensembl
  • heart development : IEA:Ensembl
  • negative regulation of osteoclast development : IEA:Ensembl
  • post-embryonic eye morphogenesis : IEA:Ensembl
  • sequestering of BMP in extracellular matrix : IEA:Ensembl
  • sequestering of TGFbeta in extracellular matrix : IEA:Ensembl
  • skeletal system development : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.