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M3YHD7

Beta-2-microglobulin (M3YHD7)

Uniprot ID M3YHD7
Protein Name Beta-2-microglobulin
Gene Name B2M
Species Mustela putorius furo (European domestic ferret) (Mustela furo)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.26
Function Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. .
GO - Molecular function
  • identical protein binding : IEA:Ensembl
GO - Biological process
  • antigen processing and presentation of endogenous peptide antigen via MHC class I : IEA:Ensembl
  • antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent : IEA:Ensembl
  • cellular response to iron(III) ion : IEA:Ensembl
  • ferric iron import : IEA:Ensembl
  • immune response : IEA:InterPro
  • iron ion homeostasis : IEA:Ensembl
  • negative regulation of neuron projection development : IEA:Ensembl
  • negative regulation of receptor binding : IEA:Ensembl
  • positive regulation of ferrous iron binding : IEA:Ensembl
  • positive regulation of receptor-mediated endocytosis : IEA:Ensembl
  • positive regulation of T cell cytokine production : IEA:Ensembl
  • positive regulation of T cell mediated cytotoxicity : IEA:Ensembl
  • positive regulation of transferrin receptor binding : IEA:Ensembl
  • protein refolding : IEA:Ensembl
  • regulation of erythrocyte differentiation : IEA:Ensembl
  • regulation of iron ion import : IEA:Ensembl
  • response to molecule of bacterial origin : IEA:Ensembl
  • T cell differentiation in thymus : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.