Annexin (M3YBX0)

Uniprot ID M3YBX0
Protein Name Annexin
Gene Name ANXA1
Species Mustela putorius furo (European domestic ferret) (Mustela furo)
Signal peptide(a) N Secretome P(b) 0.736
Function
GO - Molecular function
  • calcium ion binding : IEA:InterPro
  • calcium-dependent phospholipid binding : IEA:UniProtKB-KW
  • calcium-dependent protein binding : IEA:Ensembl
  • phospholipase A2 inhibitor activity : IEA:Ensembl
  • protein binding, bridging : IEA:Ensembl
  • structural molecule activity : IEA:Ensembl
GO - Biological process
  • actin cytoskeleton reorganization : IEA:Ensembl
  • alpha-beta T cell differentiation : IEA:Ensembl
  • arachidonic acid secretion : IEA:Ensembl
  • cellular response to glucocorticoid stimulus : IEA:Ensembl
  • cellular response to vascular endothelial growth factor stimulus : IEA:Ensembl
  • G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger : IEA:Ensembl
  • granulocyte chemotaxis : IEA:Ensembl
  • inflammatory response : IEA:Ensembl
  • keratinocyte differentiation : IEA:Ensembl
  • monocyte chemotaxis : IEA:Ensembl
  • myoblast migration involved in skeletal muscle regeneration : IEA:Ensembl
  • negative regulation of exocytosis : IEA:Ensembl
  • negative regulation of interleukin-8 secretion : IEA:Ensembl
  • negative regulation of T-helper 2 cell differentiation : IEA:Ensembl
  • neutrophil clearance : IEA:Ensembl
  • peptide cross-linking : IEA:Ensembl
  • phagocytosis : IEA:Ensembl
  • positive regulation of cell migration involved in sprouting angiogenesis : IEA:Ensembl
  • positive regulation of G1/S transition of mitotic cell cycle : IEA:Ensembl
  • positive regulation of interleukin-2 production : IEA:Ensembl
  • positive regulation of neutrophil apoptotic process : IEA:Ensembl
  • positive regulation of T cell proliferation : IEA:Ensembl
  • positive regulation of T-helper 1 cell differentiation : IEA:Ensembl
  • positive regulation of vesicle fusion : IEA:Ensembl
  • positive regulation of wound healing : IEA:Ensembl
  • regulation of cell shape : IEA:Ensembl
  • regulation of hormone secretion : IEA:Ensembl
  • regulation of inflammatory response : IEA:Ensembl
  • regulation of interleukin-1 production : IEA:Ensembl
  • regulation of leukocyte migration : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.